British Snoring & Sleep Apnoea Association

How did you do in the screening? I have a friend that is checking into this trial.

Thanks

For those who are interested,
I went to Quintiles last week and had the screening for the trial. That was a day of tests and an overnight stay. I failed on one of the blood tests and they are now rechecking the results, so did not stay for the duration which would have been a further 4 days and 3 nights.. It was well worth going to get the thorough testing and to help with what may be an important treatment for OSA. As an example the NHS had my AHI measured at 7 using the finger device which kept falling of all night and have treated me has somebody with mild OSA. The full polysomnograph test which Quintiles used measured an AHI of 34. That information alone was worth the trip.
Its not 5 star accommodation, the food is dreadful but with a laptop full of video's, work I can catch up on,internet access, a couple of books etc I will cheerfully go back. The staff are very competent, good humoured and easy to get on with and they compensate you financially for being there.
I would recommend anybody who is interested to go.

tony

Bump

the email addy doesn't work

I think this may have long since finished - but someone telephoned earlier today about drug trials so I bumped this up making the info easier to find. If anyone is interested, I'd suggest phoning Quintiles to find out what the latest situation is.

Hi All

I don't know if this is a new trial or a rerun of the original, either way I thought I would rehash an old post of mine as I have done a drugs trial with this company and thought it may be of interest


Fellow OSA suffers, I have been asked by another member to post something on the site about the Quintiles drug trial, as one of the few posters that have actually gone through it.

It is not my intention to start the debate again of the rights and wrongs of drug trials or indeed the whether people are being treated as guinea pigs for little remuneration.

My sole intention is to provide my perspective on what happened to me and what happens on the trial.

Firstly, I was not attracted by any agency I went to, Quintiles direct. I would also point out that the safety of the drug people get dosed with has already been tested on health volunteers and this is a second stage trial.

I will try and describe day by day what the trial consists of and my feeling as it went on (from memory)

I went in on a Monday lunchtime and had a basic screening, heart, blood pressure and bloods for drugs and other nasty things such as HIV and the like and they give you a full neurological scan.

Then tell you tell you if you pass the first bit of the screening, if you go straight through they give you a bed for the night and do the first overnight screening, in all honesty I can not remember what the AHI had to be but mine had gone up to 50 (from 48) and they said I was well inside .

The next day if the results of the first day and nights test are OK you are admitted properly for the trial. Other than that not much else happens on that day or night.

On the Wednesday you have the overnight screening again and if it varies (if I remember correctly) more than 40% from the first nights results you are excluded from the rest of the trial.

On the Thursday night I was dosed and was hooked up for the night again. I do know that my AHI did drop on the Thursday whether I was dosed or not. On the Friday I got off home just after lunch.

During the time they do give you a few heart traces, blood tests and BP but they are really good at them and I could not really say they caused any discomfort.

You then go back for a follow up a week or so after for some more blood tests and are you OK questions.

The staff are pretty good on the whole, but the very occasional one, I felt did treat you a little bit like you are there for the money. That is understandable when most of the people there are healthy and are only there for the money.

I think when I did the trail there had been 80 or so healthy volunteers to ensure the drug was safe and then about 12 with OSA.

I understand they are still looking for 6 volunteers to complete this phase of the study. The person to talk to for the details is Ibraheem Essack at Quintiles 0207-910-7912. Please feel free you say Phil from Shropshire suggested you contact him. He is a nice guy and will guide you through the entire process as well as being the team Neurophysiologist.

The only suggestion I would make if you decide to go for the trail is to make sure you take something to do because there are long spells of doing nothing.

As I said at the start this post is just to provide information to anyone who may be considering the trial and not to start a debate over the rights and wrongs.

Hi have spoken to the organiser of this study and it did finish some time ago. Hope this helps clear up any doubt.

Sleep well

I have suffered sleep apnoea for 20yrs. plus (diagnosed St. Georges. Tooting) never could get on with CPAP. May be available for "Drug Trial" but would like more details please.